β-Nicotinamide mononucleotide
β-Nicotinamide mononucleotide

NMN is the highly effective NAD+ precursor, known to increase cellular NAD+ production.  NAD+ is required by all living cells for the fundamental biological process that makes life possible. NAD+ declines with age.

Comprehensive information and resources are listed on our News&Research page,  where you will find the latest research, studies, peer-reviewed articles as well as historical information.

NMN increases NAD+ levels.  Higher NAD+ levels naturally counteract age-related diseases such as mitochondrial dysfunction, cardiovascular disease, neurological conditions, Alzheimer’s disease, cancer, stroke and diabetes. *
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease

Absolutely, YES!  Customer safety, health, well-being and product integrity certification is of critical importance.  NovoHealthspan products are of guaranteed purity, as per COA (Certificate Of Analysis).  Each batch is redundantly tested for purity and contaminants.  Our final certification testing COA is by Micro Quality Labs, Inc., an independent, third-party ISO 17025 FDA, EPA, DEA, CPSC, and Health Canada certified testing lab.  The results for the specific product sold are available upon asking and/or published.

IMPORTANT NOTE: a majority of NMN suppliers do not test or provide independent verification testing, and the FDA does not monitor nutraceutical quality. Buyer beware!  Obtain and verify independent third-party testing from your Nutraceutical supplier to verify what you are putting in your body!!

Sublingual (under the tongue) quick-melt delivery, in order to be effective, needs a molecular weight of less than 500 (as 29 free base) to facilitate its diffusion.  NMN molecular weight is 324, well within the best sublingual absorption range.

Sublingual delivery bypasses the Gastro-Intestinal tract and protects the NMN, the active ingredient, from degradation in the biological environment, prolongs presence in the blood and increases cellular uptake.

Our biochemical engineers specifically formulated proprietary NovoHealthspan sublingual NMN tablets to dissolve within the optimal mucosal membrane transfer time and deliver more NMN on the cellular level, avoiding the GI tract.  We successfully masked the inherently bitter taste of NMN with a pleasant, natural, orange extract flavoring.

Sublingual delivery provides:

  • Increased bioavailability. Up to 40% more NMN delivered to the cell and converted to NAD+ *
  • Protection from the hostile environment of the gastrointestinal tract.
  • Rapid delivery for faster clinical effect
  • Increased dose effectiveness, compared to ingestive delivery
  • A better alternative to swallowing pills or injections
Chart - Why is sublingual (under tongue) delivery better than tablets or capsules?

As of this writing, we have 4 scientific publications on the subject of “sublingual delivery” on our News&Research page.

NMN is the most powerful and direct NAD+ precursor supporting mitochondrial health, and thus healthy aging and DNA repair.

Research paper “Slc12a8 is a nicotinamide mononucleotide transporter”, published in Nature Metabolism, concludes that  “These results clearly demonstrate that Slc12a8 specifically transports NMN, but not NR, in the order of minutes.”

Further information on News&Research page.

Mitochondria are often referred to as the cell's "powerhouse," generating chemical energy to carry out essential biological functions. These self-contained organelles, which live inside our cells and house their own small genomes, have long been identified as key biological players in aging. As they become increasingly dysfunctional overtime, many age-related diseases set in.

Enzymes or chemicals are used to increase the rate of chemical reactions without themselves being consumed.  Enzymes are necessary to make the synthesis (manufacturing process) cost-effective by greatly decreasing process time.  Using enzymes instead of chemicals is more difficult as enzymes are very specific to each chemical reaction.  However, the advantages of using an enzymatic process are monumental:

  1. There are no residual chemicals to worry about and
  2. The enzymatic process renders the resulting compound more stable (decreasing light and temperature degradation).  NovoHealthspan strives to make our nutraceuticals as natural and organic as possible.  For further scientific reading, please see “The Cell, NCBI publication; The Central Role of Enzymes as Biological Catalysts.

That is one of the most profound questions!  You obviously need to be 100% certain about what you are ingesting, and certain that you are getting what you pay for!!

This is how you can rest assured:

  1.  Ask your supplier to provide an analysis, by a US, independent, third-party, ISO 17052 certified testing lab.  This should, at least, provide an “HPLC test” that certifies the % purity of the compound. Additionally, the test should include heavy metals (Lead, Arsenic Cadmium, Mercury).  This must be a test of the actual current batch that you are buying, not a generic analysis!  A simple Certificate Of Analysis (COA) is not sufficient, as these are usually issued by the manufacturer (and not an independent lab).
  2. Is it as natural, organic, as possible?  If the supplier states that the compound is “natural” or “stable”, ask for proof., which should come in the form of a Radiocarbon (C14) test that indicates % of natural vs. synthetic sources.
IMPORTANT NOTE: a majority of NMN suppliers do not test or provide independent verification testing, and the FDA does not monitor nutraceutical quality. Buyer beware!  Obtain and verify independent third-party testing from your Nutraceutical supplier to verify what you are putting in your body!!

Sirtuins are a family of proteins that play a role in aging by regulating cellular health. They're responsible for critical biological functions like DNA expression and aspects of aging. However, sirtuins can only function in the presence of NAD+, nicotinamide adenine dinucleotide, a coenzyme found in all living cells.

NovoHealthspan offers only the highest quality, purest, scientific research based, peer reviewed, clinically validated compounds.

All of our  compounds are manufactured in cGMP, ISO9001, Intertec compliant facilities.

Each batch is redundantly tested at the manufacturing facility, then by an independent, third-party ISO 17025 certified testing lab for purity and contaminants. Test results are either posted or will be provided by NovoHealthspan upon asking.

Your safety is of utmost importance at NovoHealthspan.